Photo biomodulation ameliorates ovarian aging by alleviating oxidative stress and inflammation damage and improving mitochondrial function (He et al. 2024).

A recent in vitro study from China, relates to Photobiomodulation Therapy for Fertility. The authors found that, “PBM (4 J/cm2) effectively recovered the levels of sex hormones, increased the number of primordial and growing follicles, improved angiogenesis, and decreased cell apoptosis in naturally aged mice. Moreover, PBM reduced oxidative stress, inhibited chronic ovarian inflammation, and improved mitochondrial function in aged ovaries. Study highlights follow:

  • Photobiomodulation improved ovarian function.
  • Photobiomodulation protected human granulosa cells from oxidative stress damage.
  • Photobiomodulation reduced oxidative stress and chronic inflammation in aged ovaries.
  • Photobiomodulation enhanced mitochondrial function of aged ovarian cells.
  • Photobiomodulation is a promising treatment to clinically restore ovarian function.

The authors conclude that Photobiomodulation Therapy for Fertility offers a promising option for women facing reproductive health issues, as a natural, non-invasive supplement, to other types of Assisted Reproductive Technology (ART).  

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